diff --git a/build/jam/BuildSetup b/build/jam/BuildSetup
index 08bd75cd1c..17d7bb945c 100644
--- a/build/jam/BuildSetup
+++ b/build/jam/BuildSetup
@@ -1369,3 +1369,20 @@ if $(HAIKU_NO_WERROR) != 1 {
 	EnableWerror src system runtime_loader ;
 }
 
+# The following directories cannot currently be compiled with DEBUG=1
+SetConfigVar DEBUG : HAIKU_TOP src add-ons disk_systems bfs : 0 : local ;
+SetConfigVar DEBUG : HAIKU_TOP src add-ons kernel drivers audio hda : 0 : local ;
+SetConfigVar DEBUG : HAIKU_TOP src add-ons kernel drivers audio ac97 auich : 0 : local ; # fails with gcc4 only
+SetConfigVar DEBUG : HAIKU_TOP src add-ons kernel drivers audio ac97 auvia : 0 : local ; # fails with gcc4 only
+SetConfigVar DEBUG : HAIKU_TOP src add-ons kernel drivers audio ac97 sis7018 : 0 : local ;
+SetConfigVar DEBUG : HAIKU_TOP src add-ons kernel file_systems btrfs : 0 : local ;
+SetConfigVar DEBUG : HAIKU_TOP src add-ons kernel file_systems ntfs libntfs : 0 : local ;
+SetConfigVar DEBUG : HAIKU_TOP src add-ons kernel file_systems udf : 0 : local ;
+SetConfigVar DEBUG : HAIKU_TOP src add-ons media media-add-ons dvb : 0 : local ;
+SetConfigVar DEBUG : HAIKU_TOP src add-ons print drivers gutenprint : 0 : local ;
+SetConfigVar DEBUG : HAIKU_TOP src bin coreutils src : 0 : local ; # fails with gcc2 only
+SetConfigVar DEBUG : HAIKU_TOP src bin network tcpdump : 0 : local ;
+SetConfigVar DEBUG : HAIKU_TOP src servers input : 0 : local ;
+SetConfigVar DEBUG : HAIKU_TOP src servers media_addon : 0 : local ;
+SetConfigVar DEBUG : HAIKU_TOP src system boot loader file_systems bfs : 0 : local ;
+SetConfigVar DEBUG : HAIKU_TOP src system boot loader file_systems tarfs : 0 : local ;